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Silencing UHRF1 Enhances Radiosensitivity of Esophageal Squamous Cell Carcinoma by Inhibiting the PI3K/Akt/mTOR Signaling Pathway

PURPOSE: Resistance to radiotherapy results in a high treatment failure rate for locally advanced esophageal squamous cell carcinoma (ESCC). Ubiquitin-like with plant homeodomain and ring-finger domains 1 (UHRF1), is associated with poor prognosis in ESCC. The present study aims to characterize the...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Hui, Beina, Pan, Shupei, Che, Shaomin, Sun, Yuchen, Yan, Yanli, Guo, Jia, Gong, Tuotuo, Ren, Juan, Zhang, Xiaozhi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8232844/
https://ncbi.nlm.nih.gov/pubmed/34188537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S311192
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