AZD2014 Radiosensitizes Oral Squamous Cell Carcinoma by Inhibiting AKT/mTOR Axis and Inducing G1/G2/M Cell Cycle Arrest

BACKGROUND: Oral squamous cell carcinoma (OSCC) is one of the most common malignant neoplasms in Taiwan. Activation of the mTOR signaling pathway has been linked to decreased radiation responsiveness in human oral cancer, thus it limits efficacy of radiotherapy. To address this question, we investig...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yu, Chih-Chia, Huang, Hsien-bin, Hung, Shih-Kai, Liao, Hui-Fen, Lee, Ching-Chih, Lin, Hon-Yi, Li, Szu-Chin, Ho, Hsu-Chueh, Hung, Chung-Lin, Su, Yu-Chieh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816280/
https://ncbi.nlm.nih.gov/pubmed/27031247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151942
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados