Dexamethasone affects cell growth/apoptosis/chemosensitivity of colon cancer via glucocorticoid receptor α/NF-κB

Glucocorticoids are effective to treat lymphoma and leukemia. Their effect in colon cancer remains far from clear. Here, we found that glucocorticoid receptor (GR) α protein level was dramatically lower in colon cancer than in lymphoma. Colon cell lines LoVo and HCT116 were GRα-rich and GRα was not...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: He, Jianming, Zhou, Jinming, Yang, Weiwen, Zhou, Qi, Liang, Xi, Pang, Xueli, Li, Jianjun, Pan, Feng, Liang, Houjie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620202/
https://ncbi.nlm.nih.gov/pubmed/28978062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18802
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