Fenofibrate potentiates chemosensitivity to human breast cancer cells by modulating apoptosis via AKT/NF-κB pathway

BACKGROUND: Cumulatively, evidences revealed that fenofibrate used in the therapy of hyperlipidemia and hypercholesterolemia has anti-cancer effect in multiple cancer types. However, its function and underlying mechanism of chemosensitization in breast cancer remain poorly understood. MATERIALS AND...

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Enregistré dans:
Détails bibliographiques
Publié dans:Onco Targets Ther
Auteurs principaux: Sun, Jianguo, Zheng, Zhibao, Chen, Qi, Pan, Yin, Quan, Mingming, Dai, Yuechu
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2019
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353220/
https://ncbi.nlm.nih.gov/pubmed/30774365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S191239
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