Celastrol ameliorates inflammation through inhibition of NLRP3 inflammasome activation

Celastrol exhibits potential anti-inflammatory activity in a variety of inflammatory diseases, but the mechanism remains poorly understood. Activation of NLRP3 inflammasome is involved in multiple inflammatory diseases. Here, we show that celastrol abolishes the NLRP3 inflammasome activation, inhibi...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Yu, Xianjun, Zhao, Qun, Zhang, Xixi, Zhang, Haiwei, Liu, Yongbo, Wu, Xiaoxia, Li, Ming, Li, Xiaoming, Zhang, Jingxuan, Ruan, Xuzhi, Zhang, Haibing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620174/
https://ncbi.nlm.nih.gov/pubmed/28978034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18619
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