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Bazedoxifene enhances the anti-tumor effects of cisplatin and radiation treatment by blocking IL-6 signaling in head and neck cancer

Recent studies have shown that IL-6 signaling plays an important role in the aggressive and metastatic phenotype of head and neck squamous cell carcinoma (HNSCC). Therefore, we hypothesized that targeting of IL-6 signaling in HNSCC could enhance the therapeutic efficacy of standard chemoradiation tr...

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Publicat a:Oncotarget
Autors principals: Yadav, Arti, Kumar, Bhavna, Teknos, Theodoros N., Kumar, Pawan
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620145/
https://ncbi.nlm.nih.gov/pubmed/28978005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11464
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