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Sorafenib enhances the anti-tumor effects of chemo-radiation treatment by down-regulating ERCC-1 and XRCC-1 DNA repair proteins
Head and neck squamous cell carcinoma (HNSCC) remains a challenging clinical problem, due to the persisting high rate of local and distant failure due to the acquisition of chemo and radio-resistance. In this study, we examined if treatment with sorafenib, a potent inhibitor of Raf kinase and VEGFR,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132282/ https://ncbi.nlm.nih.gov/pubmed/21551262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0004 |
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