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Deletion of NF-κB/RelA in Angiotensin II-sensitive mesenchymal cells blocks aortic vascular inflammation and AAA formation
OBJECTIVE: Infusion of angiotensin II (Ang II) induces extracellular matrix remodeling and inflammation resulting in abdominal aortic aneurysms (AAA) in normolipidemic mice. Although Ang II activates mesenchymal cells in the media and adventitia to become fibrogenic, the sentinel role of this mesenc...
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| 發表在: | Arterioscler Thromb Vasc Biol |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5620126/ https://ncbi.nlm.nih.gov/pubmed/28818856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309863 |
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