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Inferring Genome-Wide Functional Modulatory Network: A Case Study on NF-κB/RelA Transcription Factor

How different pathways lead to the activation of a specific transcription factor (TF) with specific effects is not fully understood. We model context-specific transcriptional regulation as a modulatory network: triplets composed of a TF, target gene, and modulator. Modulators usually affect the acti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Comput Biol
Prif Awduron: Li, Xueling, Zhu, Min, Brasier, Allan R., Kudlicki, Andrzej S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394173/
https://ncbi.nlm.nih.gov/pubmed/25844669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2014.0299
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