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Arsenite Binds to the Zinc Finger Motif of TIP60 Histone Acetyltransferase and Induces Its Degradation via the 26S Proteasome

Arsenic is a ubiquitous environmental contaminant with widespread public health concern. Epidemiological studies have revealed that chronic human exposure to arsenic in drinking water is associated with the prevalence of skin, lung, and bladder cancers. Aberrant histone modifications (e.g., methylat...

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Bibliografische gegevens
Gepubliceerd in:Chem Res Toxicol
Hoofdauteurs: Tam, Lok Ming, Jiang, Ji, Wang, Pengcheng, Li, Lin, Miao, Weili, Dong, Xuejiao, Wang, Yinsheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620024/
https://ncbi.nlm.nih.gov/pubmed/28837777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.7b00146
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