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Low Dose Inflammatory Potential of Silica Particles in Human-Derived THP-1 Macrophage Cell Culture Studies – Mechanism and Effects of Particle Size and Iron

Silica and iron are major constituents in ambient particulate matter, and iron is a common impurity in many engineered nanomaterials. The purpose of this work was to determine the pro-inflammatory and other biological effects and mechanism of particle size and iron presence under low dose, non-cytot...

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Bibliografiske detaljer
Udgivet i:Chem Biol Interact
Main Authors: Premshekharan, Gayatri, Zhang, Hongqiao, Nguyen, Kennedy, Forman, Henry Jay, Leppert, Valerie Jean
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619987/
https://ncbi.nlm.nih.gov/pubmed/28512001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2017.05.004
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