Delayed Nrf2-regulated antioxidant gene induction in response to silica nanoparticles

Silica nanoparticles with iron on their surface cause the production of oxidants and stimulate an inflammatory response in macrophages. Nuclear factor erythroid-derived 2 –like factor 2 (Nrf2) signaling and its regulated antioxidant genes play critical roles in maintaining redox homeostasis. In this...

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Bibliographic Details
Published in:Free Radic Biol Med
Main Authors: Zhang, Hongqiao, Zhou, Lulu, Yuen, Jenay, Birkner, Nancy, Leppert, Valerie, O’Day, Peggy A., Forman, Henry Jay
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480609/
https://ncbi.nlm.nih.gov/pubmed/28389405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.04.002
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