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Delayed Nrf2-regulated antioxidant gene induction in response to silica nanoparticles

Silica nanoparticles with iron on their surface cause the production of oxidants and stimulate an inflammatory response in macrophages. Nuclear factor erythroid-derived 2 –like factor 2 (Nrf2) signaling and its regulated antioxidant genes play critical roles in maintaining redox homeostasis. In this...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Zhang, Hongqiao, Zhou, Lulu, Yuen, Jenay, Birkner, Nancy, Leppert, Valerie, O’Day, Peggy A., Forman, Henry Jay
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480609/
https://ncbi.nlm.nih.gov/pubmed/28389405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.04.002
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