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Delayed Nrf2-regulated antioxidant gene induction in response to silica nanoparticles

Silica nanoparticles with iron on their surface cause the production of oxidants and stimulate an inflammatory response in macrophages. Nuclear factor erythroid-derived 2 –like factor 2 (Nrf2) signaling and its regulated antioxidant genes play critical roles in maintaining redox homeostasis. In this...

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Dades bibliogràfiques
Publicat a:Free Radic Biol Med
Autors principals: Zhang, Hongqiao, Zhou, Lulu, Yuen, Jenay, Birkner, Nancy, Leppert, Valerie, O’Day, Peggy A., Forman, Henry Jay
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480609/
https://ncbi.nlm.nih.gov/pubmed/28389405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.04.002
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