lncRNA requirements for mouse acute myeloid leukemia and normal differentiation

A substantial fraction of the genome is transcribed in a cell-type-specific manner, producing long non-coding RNAs (lncRNAs), rather than protein-coding transcripts. Here, we systematically characterize transcriptional dynamics during hematopoiesis and in hematological malignancies. Our analysis of...

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發表在:eLife
Main Authors: Delás, M Joaquina, Sabin, Leah R, Dolzhenko, Egor, Knott, Simon RV, Munera Maravilla, Ester, Jackson, Benjamin T, Wild, Sophia A, Kovacevic, Tatjana, Stork, Eva Maria, Zhou, Meng, Erard, Nicolas, Lee, Emily, Kelley, David R, Roth, Mareike, Barbosa, Inês AM, Zuber, Johannes, Rinn, John L, Smith, Andrew D, Hannon, Gregory J
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2017
主題:
Developmental Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619947/
https://ncbi.nlm.nih.gov/pubmed/28875933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25607
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