lncRNA requirements for mouse acute myeloid leukemia and normal differentiation

A substantial fraction of the genome is transcribed in a cell-type-specific manner, producing long non-coding RNAs (lncRNAs), rather than protein-coding transcripts. Here, we systematically characterize transcriptional dynamics during hematopoiesis and in hematological malignancies. Our analysis of...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Delás, M Joaquina, Sabin, Leah R, Dolzhenko, Egor, Knott, Simon RV, Munera Maravilla, Ester, Jackson, Benjamin T, Wild, Sophia A, Kovacevic, Tatjana, Stork, Eva Maria, Zhou, Meng, Erard, Nicolas, Lee, Emily, Kelley, David R, Roth, Mareike, Barbosa, Inês AM, Zuber, Johannes, Rinn, John L, Smith, Andrew D, Hannon, Gregory J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619947/
https://ncbi.nlm.nih.gov/pubmed/28875933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25607
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