Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster

Genetic variants near and within the fatty acid desaturase (FADS) cluster are associated with polyunsaturated fatty acid (PUFA) biosynthesis, levels of several disease biomarkers and risk of human disease. However, determining the functional mechanisms by which these genetic variants impact PUFA lev...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rahbar, Elaheh, Ainsworth, Hannah C., Howard, Timothy D., Hawkins, Gregory A., Ruczinski, Ingo, Mathias, Rasika, Seeds, Michael C., Sergeant, Susan, Hixson, James E., Herrington, David M., Langefeld, Carl D., Chilton, Floyd H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619705/
https://ncbi.nlm.nih.gov/pubmed/28957329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180903
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