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Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster

Genetic variants near and within the fatty acid desaturase (FADS) cluster are associated with polyunsaturated fatty acid (PUFA) biosynthesis, levels of several disease biomarkers and risk of human disease. However, determining the functional mechanisms by which these genetic variants impact PUFA lev...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Rahbar, Elaheh, Ainsworth, Hannah C., Howard, Timothy D., Hawkins, Gregory A., Ruczinski, Ingo, Mathias, Rasika, Seeds, Michael C., Sergeant, Susan, Hixson, James E., Herrington, David M., Langefeld, Carl D., Chilton, Floyd H.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619705/
https://ncbi.nlm.nih.gov/pubmed/28957329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180903
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