Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression

Omega-6 (n-6) and omega-3 (n-3) long (≥ 20 carbon) chain polyunsaturated fatty acids (LC-PUFAs) play a critical role in human health and disease. Biosynthesis of LC-PUFAs from dietary 18 carbon PUFAs in tissues such as the liver is highly associated with genetic variation within the fatty acid desat...

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Publicado en:PLoS One
Autores principales: Reynolds, Lindsay M., Howard, Timothy D., Ruczinski, Ingo, Kanchan, Kanika, Seeds, Michael C., Mathias, Rasika A., Chilton, Floyd H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874031/
https://ncbi.nlm.nih.gov/pubmed/29590160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194610
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