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Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression

Omega-6 (n-6) and omega-3 (n-3) long (≥ 20 carbon) chain polyunsaturated fatty acids (LC-PUFAs) play a critical role in human health and disease. Biosynthesis of LC-PUFAs from dietary 18 carbon PUFAs in tissues such as the liver is highly associated with genetic variation within the fatty acid desat...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Reynolds, Lindsay M., Howard, Timothy D., Ruczinski, Ingo, Kanchan, Kanika, Seeds, Michael C., Mathias, Rasika A., Chilton, Floyd H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874031/
https://ncbi.nlm.nih.gov/pubmed/29590160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194610
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