p53 regulates ERK1/2/CREB cascade via a novel SASH1/MAP2K2 crosstalk to induce hyperpigmentation

We previously reported that three point mutations in SASH1 and mutated SASH1 promote melanocyte migration in dyschromatosis universalis hereditaria (DUH) and a novel p53/POMC/Gαs/SASH1 autoregulatory positive feedback loop is regulated by SASH1 mutations to induce pathological hyperpigmentation phen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Mol Med
Egile Nagusiak: Zhou, Ding'an, Kuang, Zhongshu, Zeng, Xing, Wang, Ke, Ma, Jiangshu, Luo, Huangchao, Chen, Mei, Li, Yan, Zeng, Jiawei, Li, Shu, Luan, Fujun, He, Yong, Dai, Hongying, Liu, Beizhong, Li, Hui, He, Lin, Xing, Qinghe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618682/
https://ncbi.nlm.nih.gov/pubmed/28382689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13168
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak