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Differences in Sulfotyrosine Binding amongst CXCR1 and CXCR2 Chemokine Ligands

Tyrosine sulfation, a post-translational modification found on many chemokine receptors, typically increases receptor affinity for the chemokine ligand. A previous bioinformatics analysis suggested that a sulfotyrosine (sY)-binding site on the surface of the chemokine CXCL12 may be conserved through...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Moussouras, Natasha A., Getschman, Anthony E., Lackner, Emily R., Veldkamp, Christopher T., Dwinell, Michael B., Volkman, Brian F.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618543/
https://ncbi.nlm.nih.gov/pubmed/28869519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091894
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