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Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1α (SDF-1α/CXCL12)

Tyrosine sulfation of the chemokine receptor CXCR4 enhances its interaction with the chemokine SDF-1α. Given similar post-translational modification of other receptors, including CCR5, CX3CR1 and CCR2b, tyrosine sulfation may be of universal importance in chemokine signaling. N-terminal domains from...

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Detalhes bibliográficos
Main Authors: Veldkamp, Christopher T., Seibert, Christoph, Peterson, Francis C., Sakmar, Thomas P., Volkman, Brian F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670582/
https://ncbi.nlm.nih.gov/pubmed/16725153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.04.052
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