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Comparison of Liver Detargeting Strategies for Systemic Therapy with Oncolytic Adenovirus Serotype 5

Oncolytic viruses would ideally be of use for systemic therapy to treat disseminated cancer. To do this safely, this may require multiple layers of cancer specificity. The pharmacology and specificity of oncolytic adenoviruses can be modified by (1) physical retargeting, (2) physical detargeting, (3...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomedicines
Prif Awduron: Nguyen, Tien V., Barry, Mary E., Turner, Mallory A., Crosby, Catherine M., Trujillo, Miguel A., Morris, John C., Barry, Michael A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618304/
https://ncbi.nlm.nih.gov/pubmed/28796161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines5030046
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