A novel pathogenic single nucleotide germline deletion in APC gene in a four generation Chinese family with familial adenomatous polyposis

Familial adenomatous polyposis (FAP) is an autosomal dominant precancerous condition which is associated with germline mutations of the APC gene. Clinically, FAP is characterized by the development of multiple colorectal adenomas or polyps which finally result in colorectal cancer by the 40 years ag...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Zhao, Liang, Shengyun, Wang, Dan, Liang, Shengran, Li, Yuwei, Wang, Bingjie, jiang, Tao, Zhao, Guoru, Zhang, Xipeng, Banerjee, Santasree
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617841/
https://ncbi.nlm.nih.gov/pubmed/28955048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10395-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados