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A novel pathogenic splice acceptor site germline mutation in intron 14 of the APC gene in a Chinese family with familial adenomatous polyposis

Familial adenomatous polyposis (FAP) is an autosomal dominant precancerous condition, clinically characterized by the presence of multiple colorectal adenomas or polyps. Patients with FAP has a high risk of developing colorectal cancer (CRC) from these colorectal adenomatous polyps by the mean age o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Dan, Liang, Shengyun, Zhang, Zhao, Zhao, Guoru, Hu, Yuan, Liang, Shengran, Zhang, Xipeng, Banerjee, Santasree
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400587/
https://ncbi.nlm.nih.gov/pubmed/28423518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15570
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