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Weighted Pseudolikelihood for SNP set Analysis with Multiple Secondary Outcomes in Case-Control Genetic Association Studies
We propose a weighted pseudolikelihood method for analyzing the association of a SNP set, e.g., SNPs in a gene or a genetic pathway or network, with multiple secondary phenotypes in case-control genetic association studies. To boost analysis power, we assume that the SNP-specific effects are shared...
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| Udgivet i: | Biometrics |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617769/ https://ncbi.nlm.nih.gov/pubmed/28346824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12680 |
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