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Weighted Pseudolikelihood for SNP set Analysis with Multiple Secondary Outcomes in Case-Control Genetic Association Studies

We propose a weighted pseudolikelihood method for analyzing the association of a SNP set, e.g., SNPs in a gene or a genetic pathway or network, with multiple secondary phenotypes in case-control genetic association studies. To boost analysis power, we assume that the SNP-specific effects are shared...

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Publicat a:Biometrics
Autors principals: Sofer, Tamar, Schifano, Elizabeth D., Christiani, David C., Lin, Xihong
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617769/
https://ncbi.nlm.nih.gov/pubmed/28346824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12680
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