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Kernel Machine SNP-set Analysis for Censored Survival Outcomes in Genome-wide Association Studies

In this paper, we develop a powerful test for identifying SNP-sets that are predictive of survival with data from genome-wide association studies (GWAS). We first group typed SNPs into SNP-sets based on genomic features and then apply a score test to assess the overall effect of each SNP-set on the...

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Detalhes bibliográficos
Main Authors: Lin, Xinyi, Cai, Tianxi, Wu, Michael C., Zhou, Qian, Liu, Geoffrey, Christiani, David C., Lin, Xihong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373190/
https://ncbi.nlm.nih.gov/pubmed/21818772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20610
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