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Kernel Machine SNP-set Testing under Multiple Candidate Kernels

Joint testing for the cumulative effect of multiple single nucleotide polymorphisms grouped on the basis of prior biological knowledge has become a popular and powerful strategy for the analysis of large scale genetic association studies. The kernel machine (KM) testing framework is a useful approac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wu, Michael C., Maity, Arnab, Lee, Seunggeun, Simmons, Elizabeth M., Harmon, Quaker E., Lin, Xinyi, Engel, Stephanie M., Molldrem, Jeffrey J., Armistead, Paul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769109/
https://ncbi.nlm.nih.gov/pubmed/23471868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21715
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