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A Powerful Test for SNP Effects on Multivariate Binary Outcomes using Kernel Machine Regression

Evaluating multiple binary outcomes is common in genetic studies of complex diseases. These outcomes are often correlated because they are collected from the same individual and they may share common marker effects. In this paper, we propose a procedure to test for effect of a SNP-set on multiple, p...

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Pubblicato in:Stat Biosci
Autori principali: Davenport, Clemontina A., Maity, Arnab, Sullivan, Patrick F., Tzeng, Jung-Ying
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226013/
https://ncbi.nlm.nih.gov/pubmed/30420901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12561-017-9189-9
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