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The Generalized Higher Criticism for Testing SNP-Set Effects in Genetic Association Studies
It is of substantial interest to study the effects of genes, genetic pathways, and networks on the risk of complex diseases. These genetic constructs each contain multiple SNPs, which are often correlated and function jointly, and might be large in number. However, only a sparse subset of SNPs in a...
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| Publicat a: | J Am Stat Assoc |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5517103/ https://ncbi.nlm.nih.gov/pubmed/28736464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01621459.2016.1192039 |
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