Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells

P-element–induced wimpy testes (Piwi) proteins are known for suppressing retrotransposon activation in the mammalian germline. However, whether Piwi protein or Piwi-dependent functions occur in the mammalian soma is unclear. Contrary to germline-restricted expression, we observed that Piwi-like Miwi...

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Publicado en:J Clin Invest
Autores principales: Wasserman, Gregory A., Szymaniak, Aleksander D., Hinds, Anne C., Yamamoto, Kazuko, Kamata, Hirofumi, Smith, Nicole M.S., Hilliard, Kristie L., Carrieri, Claudia, Labadorf, Adam T., Quinton, Lee J., Ai, Xingbin, Varelas, Xaralabos, Chen, Felicia, Mizgerd, Joseph P., Fine, Alan, O’Carroll, Dónal, Jones, Matthew R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617666/
https://ncbi.nlm.nih.gov/pubmed/28920925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94639
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