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Gα13 ablation reprograms myofibers to oxidative phenotype and enhances whole-body metabolism
Skeletal muscle is a key organ in energy homeostasis owing to its high requirement for nutrients. Heterotrimeric G proteins converge signals from cell-surface receptors to potentiate or blunt responses against environmental changes. Here, we show that muscle-specific ablation of Gα13 in mice promote...
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| 發表在: | J Clin Invest |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617657/ https://ncbi.nlm.nih.gov/pubmed/28920922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92067 |
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