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Mice deficient for ERAD machinery component Sel1L develop central diabetes insipidus
Deficiency of the antidiuretic hormone arginine vasopressin (AVP) underlies diabetes insipidus, which is characterized by the excretion of abnormally large volumes of dilute urine and persistent thirst. In this issue of the JCI, Shi et al. report that Sel1L-Hrd1 ER–associated degradation (ERAD) is r...
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| Yayımlandı: | J Clin Invest |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617649/ https://ncbi.nlm.nih.gov/pubmed/28920918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96839 |
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