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Mice deficient for ERAD machinery component Sel1L develop central diabetes insipidus
Deficiency of the antidiuretic hormone arginine vasopressin (AVP) underlies diabetes insipidus, which is characterized by the excretion of abnormally large volumes of dilute urine and persistent thirst. In this issue of the JCI, Shi et al. report that Sel1L-Hrd1 ER–associated degradation (ERAD) is r...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617649/ https://ncbi.nlm.nih.gov/pubmed/28920918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96839 |
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