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Orphan nuclear receptor Nur77 inhibits poly (I:C)-triggered acute liver inflammation by inducing the ubiquitin-editing enzyme A20

Inflammation is a key contributor to various types of acute and chronic liver disease. We recently reported that lack of Nur77, an orphan nuclear receptor, contributes to the pathogenesis of inflammatory diseases including inflammatory bowel disease and sepsis. However, whether Nur77 plays a critica...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Xiu-Ming, Yang, Tian-Yu, He, Xiao-Shun, Wang, Jing-Ru, Gan, Wen-Juan, Zhang, Shen, Li, Jian-Ming, Wu, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617403/
https://ncbi.nlm.nih.gov/pubmed/28977843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17731
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