Modulation of Orphan Nuclear Receptor Nur77-mediated Apoptotic Pathway by Acetylshikonin and Analogs

Shikonin derivatives, which are the active components of the medicinal plant Lithospermum erythrorhizon, exhibit many biological effects including apoptosis induction through undefined mechanisms. We recently discovered that orphan nuclear receptor Nur77 migrates from the nucleus to mitochondria, wh...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Jie, Zhou, Wen, Li, Shao-Shun, Sun, Zhe, Lin, Bingzhen, Lang, Yuan-Yuan, He, Jia-You, Cao, Xihua, Yan, Tingdong, Wang, Li, Lu, Jiongming, Han, Young-Hoon, Cao, Yu, Zhang, Xiao-kun, Zeng, Jin-Zhang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679687/
https://ncbi.nlm.nih.gov/pubmed/18974131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1972
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