Modulation of Orphan Nuclear Receptor Nur77-mediated Apoptotic Pathway by Acetylshikonin and Analogs

Shikonin derivatives, which are the active components of the medicinal plant Lithospermum erythrorhizon, exhibit many biological effects including apoptosis induction through undefined mechanisms. We recently discovered that orphan nuclear receptor Nur77 migrates from the nucleus to mitochondria, wh...

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Detalhes bibliográficos
Main Authors: Liu, Jie, Zhou, Wen, Li, Shao-Shun, Sun, Zhe, Lin, Bingzhen, Lang, Yuan-Yuan, He, Jia-You, Cao, Xihua, Yan, Tingdong, Wang, Li, Lu, Jiongming, Han, Young-Hoon, Cao, Yu, Zhang, Xiao-kun, Zeng, Jin-Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679687/
https://ncbi.nlm.nih.gov/pubmed/18974131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1972
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