Sirtuin 6 inhibits epithelial to mesenchymal transition during idiopathic pulmonary fibrosis via inactivating TGF-β1/Smad3 signaling

Sirt6 which is implicated in the control of aging, cancer, and metabolism, has been shown to have anti-fibrosis function in heart and liver. However, whether Sirt6 inhibits idiopathic pulmonary fibrosis remains elusive. Epithelial to mesenchymal transition has been found to be involved in the pathog...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Tian, Kunming, Chen, Panpan, Liu, Zhiping, Si, Shutian, Zhang, Qian, Mou, Yong, Han, Lianyong, Wang, Qin, Zhou, Xue
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2017
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617402/
https://ncbi.nlm.nih.gov/pubmed/28977842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17723
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