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Integration of TGF-β/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

Epithelial-to-mesenchymal transitions (EMTs) underlie cell plasticity required in embryonic development and frequently observed in advanced carcinogenesis. Transforming growth factor-β (TGF-β) induces EMT phenotypes in epithelial cells in vitro and has been associated with EMT in vivo. Here we repor...

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Main Authors: Zavadil, Jiri, Cermak, Lukas, Soto-Nieves, Noemi, Böttinger, Erwin P
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC380966/
https://ncbi.nlm.nih.gov/pubmed/14976548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600069
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