Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury

We report the characterization of a novel class of lipid mediators termed elovanoids (ELVs) (ELV-N32 and ELV-N34), which are dihydroxylated derivatives of 32:6n3 and 34:6n3, respectively. The precursors of ELVs are made by elongation of a 22:6n3 fatty acid and catalyzed by ELOVL4 (elongation of very...

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Vydáno v:Sci Adv
Hlavní autoři: Bhattacharjee, Surjyadipta, Jun, Bokkyoo, Belayev, Ludmila, Heap, Jessica, Kautzmann, Marie-Audrey, Obenaus, Andre, Menghani, Hemant, Marcell, Shawn J., Khoutorova, Larissa, Yang, Rong, Petasis, Nicos A., Bazan, Nicolas G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2017
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617374/
https://ncbi.nlm.nih.gov/pubmed/28959727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1700735
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