Elovanoids counteract oligomeric β-amyloid-induced gene expression and protect photoreceptors

The onset of neurodegenerative diseases activates inflammation that leads to progressive neuronal cell death and impairments in cognition (Alzheimer’s disease) and sight (age-related macular degeneration [AMD]). How neuroinflammation can be counteracted is not known. In AMD, amyloid β-peptide (Aβ) a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Do, Khanh V., Kautzmann, Marie-Audrey I., Jun, Bokkyoo, Gordon, William C., Nshimiyimana, Robert, Yang, Rong, Petasis, Nicos A., Bazan, Nicolas G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883841/
https://ncbi.nlm.nih.gov/pubmed/31712409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912959116
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