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Epigenetic control via allosteric regulation of mammalian protein arginine methyltransferases
Arginine methylation on histones is a central player in epigenetics and in gene activation and repression. Protein arginine methyltransferase (PRMT) activity has been implicated in stem cell pluripotency, cancer metastasis, and tumorigenesis. The expression of one of the nine mammalian PRMTs, PRMT5,...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617285/ https://ncbi.nlm.nih.gov/pubmed/28874563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706978114 |
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