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Protein Arginine Methyltransferase Product Specificity Is Mediated by Distinct Active-site Architectures

In the family of protein arginine methyltransferases (PRMTs) that predominantly generate either asymmetric or symmetric dimethylarginine (SDMA), PRMT7 is unique in producing solely monomethylarginine (MMA) products. The type of methylation on histones and other proteins dictates changes in gene expr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jain, Kanishk, Warmack, Rebeccah A., Debler, Erik W., Hadjikyriacou, Andrea, Stavropoulos, Peter, Clarke, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000077/
https://ncbi.nlm.nih.gov/pubmed/27387499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740399
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