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Protein Arginine Methyltransferase Product Specificity Is Mediated by Distinct Active-site Architectures

In the family of protein arginine methyltransferases (PRMTs) that predominantly generate either asymmetric or symmetric dimethylarginine (SDMA), PRMT7 is unique in producing solely monomethylarginine (MMA) products. The type of methylation on histones and other proteins dictates changes in gene expr...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Jain, Kanishk, Warmack, Rebeccah A., Debler, Erik W., Hadjikyriacou, Andrea, Stavropoulos, Peter, Clarke, Steven G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000077/
https://ncbi.nlm.nih.gov/pubmed/27387499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740399
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