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Substrate Specificity of Human Protein Arginine Methyltransferase 7 (PRMT7): THE IMPORTANCE OF ACIDIC RESIDUES IN THE DOUBLE E LOOP

Protein arginine methyltransferase 7 (PRMT7) methylates arginine residues on various protein substrates and is involved in DNA transcription, RNA splicing, DNA repair, cell differentiation, and metastasis. The substrate sequences it recognizes in vivo and the enzymatic mechanism behind it, however,...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Feng, You, Hadjikyriacou, Andrea, Clarke, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239614/
https://ncbi.nlm.nih.gov/pubmed/25294873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.609271
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