First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor

The polycomb repressive complex 2 (PRC2) histone methyltransferase plays a central role in epigenetic regulation in development and in cancer, and hence to interrogate its role in a specific developmental transition, methods are needed for disrupting function of the complex with high temporal and sp...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Moody, James D., Levy, Shiri, Mathieu, Julie, Xing, Yalan, Kim, Woojin, Dong, Cheng, Tempel, Wolfram, Robitaille, Aaron M., Dang, Luke T., Ferreccio, Amy, Detraux, Damien, Sidhu, Sonia, Zhu, Licheng, Carter, Lauren, Xu, Chao, Valensisi, Cristina, Wang, Yuliang, Hawkins, R. David, Min, Jinrong, Moon, Randall T., Orkin, Stuart H., Baker, David, Ruohola-Baker, Hannele
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2017
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617284/
https://ncbi.nlm.nih.gov/pubmed/28864533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706907114
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