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A two-helix motif positions the active site of lysophosphatidic acid acyltransferase for catalysis within the membrane bilayer
Phosphatidic acid is the central intermediate in membrane phospholipid synthesis and is generated by two acyltransferases in a pathway conserved in all life forms. The second step in this pathway is catalyzed by 1-acyl-sn-glycero-3-phosphate acyltransferase, called PlsC in bacteria. The crystal stru...
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| Veröffentlicht in: | Nat Struct Mol Biol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5616210/ https://ncbi.nlm.nih.gov/pubmed/28714993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3436 |
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