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A two-helix motif positions the active site of lysophosphatidic acid acyltransferase for catalysis within the membrane bilayer

Phosphatidic acid is the central intermediate in membrane phospholipid synthesis and is generated by two acyltransferases in a pathway conserved in all life forms. The second step in this pathway is catalyzed by 1-acyl-sn-glycero-3-phosphate acyltransferase, called PlsC in bacteria. The crystal stru...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Struct Mol Biol
Prif Awduron: Robertson, Rosanna M., Yao, Jiangwei, Gajewski, Stefan, Kumar, Gyanendra, Martin, Erik W., Rock, Charles O., White, Stephen W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5616210/
https://ncbi.nlm.nih.gov/pubmed/28714993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3436
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