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Most Do, but Some Do Not: CD4(+)CD25(−) T Cells, but Not CD4(+)CD25(+) Treg Cells, Are Cytolytic When Redirected by a Chimeric Antigen Receptor (CAR)
Evidences are accumulating that CD4(+) T cells can physiologically mediate antigen specific target cell lysis. By circumventing major histocompatibility complex (MHC)-restrictions through an engineered chimeric antigen receptor (CAR), CD4(+) T cells lyse defined target cells as efficiently as do CD8...
שמור ב:
| הוצא לאור ב: | Cancers (Basel) |
|---|---|
| Main Authors: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
MDPI
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5615327/ https://ncbi.nlm.nih.gov/pubmed/28850063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9090112 |
| תגים: |
הוספת תג
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