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Radiofluorination of a NHC–PF(5) adduct: toward new probes for (18)F PET imaging

The radiofluorination of N-heterocyclic carbene (NHC) phosphorus(V) fluoride adducts has been investigated. The results show that the IMe-PF(5) derivative (IMe = 1,3-dimethylimidazol-2-ylidene) undergoes a Lewis acid promoted (18)F–(19)F isotopic exchange. The resulting radiofluorinated probe is rem...

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Bibliografiske detaljer
Udgivet i:Chem Commun (Camb)
Main Authors: Vabre, Boris, Chansaenpak, Kantapat, Wang, Mengzhe, Wang, Hui, Li, Zibo, Gabbaï, François P.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615223/
https://ncbi.nlm.nih.gov/pubmed/28731482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc04402j
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