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Phospho-regulation of soma-to-axon transcytosis of neurotrophin receptors

Axonal targeting of signaling receptors is essential for neuronal responses to extracellular cues. Here, we report that retrograde signaling by target-derived Nerve Growth Factor (NGF) is necessary for soma-to-axon transcytosis of TrkA receptors in sympathetic neurons, and define the molecular under...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Yamashita, Naoya, Joshi, Rajshri, Zhang, Sheng, Zhang, Zhong-Yin, Kuruvilla, Rejji
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614868/
https://ncbi.nlm.nih.gov/pubmed/28919207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.08.009
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